Anaphylactic shock is a life-threatening condition which needs detailed and mediculous clinical assessment and thoughtful treatment.Several causes can join forces in order to degranulate mast cells.Amiodarone which is an iodine-containing highly lipophilic huge handlebar mustache benzofuran can induce allergic reactions and anaphylactic shock in sensitized patients.Epinephrine is a life saving drug, but in sulfite allergic patients it should be given with caution due its wes audio 1176 metabisulfite preservative.
Metals covering cardiac defibrillators and pacemakers can act as antigens attached to serum proteins and induce allergic reactions.In anaphylactic shock, myocardial involvement due to vasospasm-induced coronary blood flow reduction manifesting as Kounis syndrome should be always considered.Clinically, combined treatment targeting the primary cause of anaphylaxis together with protection of cardiac tissue seems to be of paramount importance.