Prostate epithelial basal cells are highly plastic in their luminal differentiation capability.Basal stem cells actively produce luminal cells during organogenesis, but become restricted in the adult prostate unless receiving oncogenic or inflammatory stimuli.Given that the number of luminal cells increases relative to basal cells through developme
Combined etiology of anaphylactic cardiogenic shock: Amiodarone, epinephrine, cardioverter defibrillator, left ventricular assist devices and the Kounis syndrome
Anaphylactic shock is a life-threatening condition which needs detailed and mediculous clinical assessment and thoughtful treatment.Several causes can join forces in order to degranulate mast cells.Amiodarone which is an iodine-containing highly lipophilic huge handlebar mustache benzofuran can induce allergic reactions and anaphylactic shock in se
Pleiotrophin Interaction with Synthetic Glycosaminoglycan Mimetics
Chondroitin sulfate (CS) E is the natural ligand for pleiotrophin (PTN) in the central nervous system (CNS) of the embryo.Some structures of PTN in solution santo and johnny vinyl have been solved, but no precise location of the binding site has been reported yet.Using 15N-labelled PTN and HSQC NMR experiments, we studied the interactions with a sy
Nail Plate Constructs: A Novel Technique for Treatment of Unstable Charcot Ankle and Hindfoot Deformity
Category: Hindfoot; Diabetes Introduction/Purpose: Charcot arthropathy is a disorder known to have poor outcomes with a high risk of amputation.Life expectancy, lifetime amputation rates and five-year mortality rates approach 50%.Patients often present with multiple medical comorbidities, poor bone quality and severe deformity.They have difficulty